JmjC domain proteins modulate circadian behaviors and sleep in Drosophila
نویسندگان
چکیده
منابع مشابه
Circadian Rhythms and Sleep in Drosophila melanogaster.
The advantages of the model organism Drosophila melanogaster, including low genetic redundancy, functional simplicity, and the ability to conduct large-scale genetic screens, have been essential for understanding the molecular nature of circadian (∼24 hr) rhythms, and continue to be valuable in discovering novel regulators of circadian rhythms and sleep. In this review, we discuss the current u...
متن کاملFatty-Acid Binding Proteins Modulate Sleep and Enhance Long-Term Memory Consolidation in Drosophila
Sleep is thought to be important for memory consolidation, since sleep deprivation has been shown to interfere with memory processing. However, the effects of augmenting sleep on memory formation are not well known, and testing the role of sleep in memory enhancement has been limited to pharmacological and behavioral approaches. Here we test the effect of overexpressing the brain-type fatty aci...
متن کاملHistamine and its receptors modulate temperature-preference behaviors in Drosophila.
Temperature profoundly influences various life phenomena, and most animals have developed mechanisms to respond properly to environmental temperature fluctuations. To identify genes involved in sensing ambient temperature and in responding to its change, >27,000 independent P-element insertion mutants of Drosophila were screened. As a result, we found that defects in the genes encoding for prot...
متن کاملCircadian and Geotactic Behaviors: Genetic Pleiotropy in Drosophila Melanogaster
Data presented in this paper test the hypotheses that Hirsch’s positive geotaxis (Lo) and negative geotaxis (Hi5) strains of Drosophila melanogaster (fruit fly) differ in length of the free-running circadian activity period (tau) as well as adult geotaxis. Several genes have been shown to alter geotaxis in Drosophila. Two of these genes, cryptochrome (cry) and Pigment-dispersing-factor (Pdf) ar...
متن کاملLarge Ventral Lateral Neurons Modulate Arousal and Sleep in Drosophila
BACKGROUND Large ventral lateral clock neurons (lLNvs) exhibit higher daytime-light-driven spontaneous action-potential firing rates in Drosophila, coinciding with wakefulness and locomotor-activity behavior. To determine whether the lLNvs are involved in arousal and sleep/wake behavior, we examined the effects of altered electrical excitation of the LNvs. RESULTS LNv-hyperexcited flies rever...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Scientific Reports
سال: 2018
ISSN: 2045-2322
DOI: 10.1038/s41598-017-18989-1